








Matrix Patches
Transdermal Drug Delivery Systems (TDS/TTS) are highly effective innovative multilayer drug dosage forms applied to the skin.
Matrix Patches have the API (Active Ingredient) embedded in a matrix, which is released through the skin into the bloodstream over a certain period of time avoiding the first-pass effect, offering thus a patient-friendly alternative to classic oral dosage forms.
Final packaging of the Patches provides safe use and protecting until the point of use with respect to the laminate behaviours. Typically packaging elements like humidity, choice of packaging material, packaging design and appropriate opening features combined with intuitive handling are key elements to consider.
In general Matrix Patches are individually packed in Four Side Sealed Pouches or Sachets with our without Tear Notch for easy opening.

Different designs of Matrix Patches

On the market you find Classic Matrix Patches as one-day patch without or with Dimples and overlapping release liner or as a several-day patch as Overtape Patch.
Overlay Patches have a special overlay to avoid the patch sticking to the pouch material.
Having a long year experience in the field of manufacturing of matrix patches RCA Bignami can supply different solutions according to the material behaviour and product requirements.



Cutting
All Cutting processes in the field of web converting require high quality and precision of the cutting tools to ensure high accuracy during production.
RCA Bignami can supply different cutting tools and technologies for different applications.
Other core processes such as lamination, delamination, or sealing are individually combined to meet the needs of our customers and their products.


Scalable processes
Due to the modular and flexible design RCA Bignami offer solutions suitable for transdermal systems of different design and sizes. All RCA machines will be individually designed according to the product and customer requirements.
Core processes such as cutting, lamination, delamination, punching, sealing are indivudally combined to meet the needs of our customers and their products.
manufacturing processes
Are you interested to learn more about our Converting Processes?